- Benign, locally aggressive odontogenic tumor. Usually it slowly grows as painless swelling of the affected site.
- It can occur at any age.
- Localized invasion into the surrounding bone.
- 80-95% in the mandible (posterior body, ramus region). In the maxilla mostly in the premolar-molar region.
- Unilocular (small lesions). Multilocular (large discrete areas or honeycomb appearance)
- Smooth, well-defined, well-corticated margins
- Adjacent teeth are often displaced and resorbed.
- It causes extensive bone expansion.
- Incomplete removal can result in recurrence.
Ameloblastoma (multilocular)

Features
Differential diagnosis
- Giant cell granuloma, central (multilocular)
- Odontogenic fibroma, central
- Odontogenic keratocyst (multilocular)
- Odontogenic myxoma