Metastatic tumors (multiple)
- Metastatic tumors in the jaws are usually arise from primary lesions below the clavicle (breast, bronchus, kidney, thyroid and prostate) .
- Metastatic tumors are more common in patients over 50 years of age.
- The mandible is the most common disease site followed by the maxillary sinus
- Lesion margins are usually well-defined but not corticated. Then gradually coalesce to form large ill-defined radiolucensies. Prostate and breast tumors may stimulate bone formation and periosteal reaction resulting in a mixed (osteolytic- osteosclerotic) lesion.
- Symptoms and signs include pain, swelling, teeth mobility,paraesthesia/anaesthesia. Large lesions can lead to pathological fractures.