- It is a multifocal malignancy of the plasma cells.
- It is the most common malignancy of bone in adults. It occurs between the ages 35-70 with a mean age of 60 years.
- Lesion margins are usually well-defined but not corticated (punched-out). Some lesions may appear ragged and infiltrative. As the disease progresses the multiple radiolucencies may form a large single lesion with ill defined borders and cortex infiltration.
- Multiple round radiolucencies in the skull and jaws (more often in the mandible).
- Symptoms and signs include pain, swelling, paraesthesia, soft tissue mass and tooth mobility. Large lesions can lead to pathological fractures.