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Osteogenic sarcoma (osteosarcoma)

Osteogenic sarcoma (osteosarcoma)

  • Primary malignant tumor of bone. The most common malignancy of osseous tissue
  • Peak age of occurrence in the facial bones is 20-40 years old.
  • Oral manifestations: Pain and swelling of the involved bone, loose teeth, paresthesia, bleeding, nasal obstruction.
  • An early radiographic finding is the widening of the periadontal ligament space.
  • There are three main types:
    • Osteolytic – no neoplastic bone formation: poorly defined moth-eaten radiolucency, loosening of associated teeth
    • Mixed – patches of neoplastic bone formed within a poorly defined radiolucency with variable internal radiopacity.
    • Osteosclerotic- neoplastic bone formation: often formation of sub-periosteal bone orientated at right angles to the original cortex, producing the so-called sun-ray appearance, loosening of associated teeth, distortion of the alveolar ridge.

Differential diagnosis


Sclerotic type of osteogenic sarcoma (sun-ray appearance).

Osteolytic type of osteogenic sarcoma

Case of osteogenic sarcoma of osteolytic type with typical sun-ray periosteal reaction.