Osteogenic sarcoma (mixed)
- Primary malignant tumor of bone. The most common malignancy of bone tissue.
- Peak age of occurrence in the facial bones is 20-40 years old.
- Oral manifestations: Pain and swelling of the involved bone, loose teeth, paresthesia, bleeding, nasal obstruction.
- An early manifestation is the widening of the periadontal ligament space.
- There are three main types:
- Osteolytic – no neoplastic bone formation: poorly defined (moth-eaten) radiolucency, loosening of associated teeth
- Mixed – patches of neoplastic bone formed: poorly defined radiolucent area with variable internal radiopacity.
- Osteosclerotic- neoplastic bone formation: often formation of sub-periosteal bone orientated at right angles to the original cortex, producing the so-called sun-ray appearance, loosening of associated teeth, distortion of the alveolar ridge.