- Malignant neoplasms of haemopoietic stem cells.
- Acute cases are usually seen in children and chronic cases in those of 25 to 60 years old.
- Signs and symptoms include: splinomegaly, bleeding, bone pain, gingival inflammation, loose teeth, ulceration.
- Radiographic changes are more common in the acute type: Premature loss of teeth. Loss of lamina dura. Periapical radiolucency similar to periodontal disease. Single layer of periosteal new bone formation on the inferior border of the mandible. Multiple punched-out radiolucencies.
Leukemia
