Multiple myeloma

Features

  • It is a multifocal cancer of the plasma cells.
  • The most common malignancy of bone in adults.
    It occurs in adults older than 30 years.
  • Multiple round radiolucencies in the skull and jaws (more often in the mandible).
  • Lesion margins are usually well-defined but not corticated (punched-out)
  • Symptoms and signs include pain, swelling, paraesthesia, soft tissue mass and tooth mobility. Large lesions can lead to pathological fractures.

Differential diagnosis

Cases

Multiple myeloma

Multiple myeloma

Courtesy of Prof. CJ. Nortje, Univ. of Stellenbosch, S. Africa.