Odontogenic keratocyst (multilocular)


  • It is lined by keratinizing epithelium.
  • It is usually located in the mandible (posterior body and ramus region).
  • It can occur at any age but most develop during the second and third decade.
  • It can become very large. It extends along the body of the mandible causing minimal mediolateral expansion.
  • Unilocular (often with scalloped margins) or multilocular (more often in larger lesions).
  • Smooth margins, well-defined, often well-corticated.
  • Tendency for recurrence after inadequate surgery.
  • Adjacent teeth: vital, rarely resorbed.

Differential diagnosis


Panoramic images: Three cases of Odontogenic keratocyst (multilocular)

CBCT images: Two different cases of a large odontogenic keratocyst on the left side of the mandible.

Large odontogenic keratocyst on the right side of the mandible.

Odontogenic keratocysts in upper and lower jaw.